Sleep deprivation regulates availability of PrP(C) and Aβ peptides which can impair interaction between PrP(C) and laminin and neuronal plasticity

PrP(C) is a glycoprotein capable to interact with several molecules and mediates diverse signaling pathways. Among numerous ligands, laminin (LN) is known to promote neurite outgrowth and memory consolidation, while amyloid‐beta oligomers (Aβo) trigger synaptic dysfunction. In both pathways, mGluR1...

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Detalles Bibliográficos
Autores principales: da Luz, Marcio H. M., Pino, Jessica M. V., Santos, Tiago G., Antunes, Hanna K. M., Martins, Vilma R., de Souza, Altay A. L., Torquato, Ricardo J. S., Lee, Kil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383904/
https://www.ncbi.nlm.nih.gov/pubmed/31950499
http://dx.doi.org/10.1111/jnc.14960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383904/
https://www.ncbi.nlm.nih.gov/pubmed/31950499
http://dx.doi.org/10.1111/jnc.14960

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