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Key Intermediate Species Reveal the Copper(II)‐Exchange Pathway in Biorelevant ATCUN/NTS Complexes

The amino‐terminal copper and nickel/N‐terminal site (ATCUN/NTS) present in proteins and bioactive peptides exhibits high affinity towards Cu(II) ions and have been implicated in human copper physiology. Little is known, however, about the rate and exact mechanism of formation of such complexes. We...

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Detalles Bibliográficos
Autores principales: Kotuniak, Radosław, Strampraad, Marc J. F., Bossak‐Ahmad, Karolina, Wawrzyniak, Urszula E., Ufnalska, Iwona, Hagedoorn, Peter‐Leon, Bal, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383912/
https://www.ncbi.nlm.nih.gov/pubmed/32267054
http://dx.doi.org/10.1002/anie.202004264