Cargando…
Key Intermediate Species Reveal the Copper(II)‐Exchange Pathway in Biorelevant ATCUN/NTS Complexes
The amino‐terminal copper and nickel/N‐terminal site (ATCUN/NTS) present in proteins and bioactive peptides exhibits high affinity towards Cu(II) ions and have been implicated in human copper physiology. Little is known, however, about the rate and exact mechanism of formation of such complexes. We...
Autores principales: | Kotuniak, Radosław, Strampraad, Marc J. F., Bossak‐Ahmad, Karolina, Wawrzyniak, Urszula E., Ufnalska, Iwona, Hagedoorn, Peter‐Leon, Bal, Wojciech |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383912/ https://www.ncbi.nlm.nih.gov/pubmed/32267054 http://dx.doi.org/10.1002/anie.202004264 |
Ejemplares similares
-
Reactive Cu(2+)-peptide intermediates revealed by kinetic studies gain relevance by matching time windows in copper metallomics
por: Kotuniak, Radosław, et al.
Publicado: (2023) -
The Palladium(II) Complex of Aβ(4−16) as Suitable Model for Structural Studies of Biorelevant Copper(II) Complexes of N-Truncated Beta-Amyloids
por: Mital, Mariusz, et al.
Publicado: (2020) -
Intermediate Cu(II)-Thiolate Species in the Reduction
of Cu(II)GHK by Glutathione: A Handy Chelate for Biological Cu(II)
Reduction
por: Ufnalska, Iwona, et al.
Publicado: (2021) -
Incorporation of β‐Alanine in Cu(II) ATCUN Peptide Complexes Increases ROS Levels, DNA Cleavage and Antiproliferative Activity
por: Heinrich, Julian, et al.
Publicado: (2021) -
Redox Activity of Copper(II) Complexes with NSFRY Pentapeptide and Its Analogues
por: Wiloch, Magdalena Zofia, et al.
Publicado: (2016)