Synthesis, Radiosynthesis and Biological Evaluation of Buprenorphine‐Derived Phenylazocarboxamides as Novel μ‐Opioid Receptor Ligands

Targeted structural modifications have led to a novel type of buprenorphine‐derived opioid receptor ligand displaying an improved selectivity profile for the μ‐OR subtype. On this basis, it is shown that phenylazocarboxamides may serve as useful bioisosteric replacements for the widely occurring cin...

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Detalles Bibliográficos
Autores principales: Krüll, Jasmin, Fehler, Stefanie K., Hofmann, Laura, Nebel, Natascha, Maschauer, Simone, Prante, Olaf, Gmeiner, Peter, Lanig, Harald, Hübner, Harald, Heinrich, Markus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383964/
https://www.ncbi.nlm.nih.gov/pubmed/32378310
http://dx.doi.org/10.1002/cmdc.202000180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383964/
https://www.ncbi.nlm.nih.gov/pubmed/32378310
http://dx.doi.org/10.1002/cmdc.202000180

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