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Phenotyping Reveals Targets of a Pseudo‐Natural‐Product Autophagy Inhibitor

Pseudo‐natural‐product (NP) design combines natural product fragments to provide unprecedented NP‐inspired compounds not accessible by biosynthesis, but endowed with biological relevance. Since the bioactivity of pseudo‐NPs may be unprecedented or unexpected, they are best evaluated in target agnost...

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Detalles Bibliográficos
Autores principales: Foley, Daniel J., Zinken, Sarah, Corkery, Dale, Laraia, Luca, Pahl, Axel, Wu, Yao‐Wen, Waldmann, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383971/
https://www.ncbi.nlm.nih.gov/pubmed/32108411
http://dx.doi.org/10.1002/anie.202000364