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Phenotyping Reveals Targets of a Pseudo‐Natural‐Product Autophagy Inhibitor
Pseudo‐natural‐product (NP) design combines natural product fragments to provide unprecedented NP‐inspired compounds not accessible by biosynthesis, but endowed with biological relevance. Since the bioactivity of pseudo‐NPs may be unprecedented or unexpected, they are best evaluated in target agnost...
Autores principales: | Foley, Daniel J., Zinken, Sarah, Corkery, Dale, Laraia, Luca, Pahl, Axel, Wu, Yao‐Wen, Waldmann, Herbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383971/ https://www.ncbi.nlm.nih.gov/pubmed/32108411 http://dx.doi.org/10.1002/anie.202000364 |
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