Comparison of In Vitro and In Vivo Percutaneous Absorption Across Human Skin Using BAY1003803 Formulated as Ointment and Cream

Direct comparisons between skin absorption data and clinical pharmacokinetic data are rare. Here we use the lipophilic nonsteroidal selective glucocorticoid receptor agonist BAY1003803 to make such a comparison. The objective is to find the extent to which measurements of skin permeation in vitro ca...

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Detalles Bibliográficos
Autores principales: Günther, Clemens, Kowal, Kristin, Schmidt, Timm, Jambrecina, Alen, Toner, Frank, Nave, Rüdiger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383986/
https://www.ncbi.nlm.nih.gov/pubmed/31647607
http://dx.doi.org/10.1002/cpdd.736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383986/
https://www.ncbi.nlm.nih.gov/pubmed/31647607
http://dx.doi.org/10.1002/cpdd.736

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