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Comparison of In Vitro and In Vivo Percutaneous Absorption Across Human Skin Using BAY1003803 Formulated as Ointment and Cream
Direct comparisons between skin absorption data and clinical pharmacokinetic data are rare. Here we use the lipophilic nonsteroidal selective glucocorticoid receptor agonist BAY1003803 to make such a comparison. The objective is to find the extent to which measurements of skin permeation in vitro ca...
Autores principales: | Günther, Clemens, Kowal, Kristin, Schmidt, Timm, Jambrecina, Alen, Toner, Frank, Nave, Rüdiger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383986/ https://www.ncbi.nlm.nih.gov/pubmed/31647607 http://dx.doi.org/10.1002/cpdd.736 |
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