Synthesis of All‐Carbon Disubstituted Bicyclo[1.1.1]pentanes by Iron‐Catalyzed Kumada Cross‐Coupling

1,3‐Disubstituted bicyclo[1.1.1]pentanes (BCPs) are important motifs in drug design as surrogates for p‐substituted arenes and alkynes. Access to all‐carbon disubstituted BCPs via cross‐coupling has to date been limited to use of the BCP as the organometallic component, which restricts scope due to...

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Detalles Bibliográficos
Autores principales: Nugent, Jeremy, Shire, Bethany R., Caputo, Dimitri F. J., Pickford, Helena D., Nightingale, Frank, Houlsby, Ian T. T., Mousseau, James J., Anderson, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383991/
https://www.ncbi.nlm.nih.gov/pubmed/32346946
http://dx.doi.org/10.1002/anie.202004090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383991/
https://www.ncbi.nlm.nih.gov/pubmed/32346946
http://dx.doi.org/10.1002/anie.202004090

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