Reductive Deamination with Hydrosilanes Catalyzed by B(C(6)F(5))(3)

The strong boron Lewis acid tris(pentafluorophenyl)borane B(C(6)F(5))(3) is known to catalyze the dehydrogenative coupling of certain amines and hydrosilanes at elevated temperatures. At higher temperature, the dehydrogenation pathway competes with cleavage of the C−N bond and defunctionalization is...

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Detalles Bibliográficos
Autores principales: Fang, Huaquan, Oestreich, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384015/
https://www.ncbi.nlm.nih.gov/pubmed/32311213
http://dx.doi.org/10.1002/anie.202004651
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author Fang, Huaquan
Oestreich, Martin
author_facet Fang, Huaquan
Oestreich, Martin
author_sort Fang, Huaquan
collection PubMed
description The strong boron Lewis acid tris(pentafluorophenyl)borane B(C(6)F(5))(3) is known to catalyze the dehydrogenative coupling of certain amines and hydrosilanes at elevated temperatures. At higher temperature, the dehydrogenation pathway competes with cleavage of the C−N bond and defunctionalization is obtained. This can be turned into a useful methodology for the transition‐metal‐free reductive deamination of a broad range of amines as well as heterocumulenes such as an isocyanate and an isothiocyanate.
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spelling pubmed-73840152020-07-28 Reductive Deamination with Hydrosilanes Catalyzed by B(C(6)F(5))(3) Fang, Huaquan Oestreich, Martin Angew Chem Int Ed Engl Communications The strong boron Lewis acid tris(pentafluorophenyl)borane B(C(6)F(5))(3) is known to catalyze the dehydrogenative coupling of certain amines and hydrosilanes at elevated temperatures. At higher temperature, the dehydrogenation pathway competes with cleavage of the C−N bond and defunctionalization is obtained. This can be turned into a useful methodology for the transition‐metal‐free reductive deamination of a broad range of amines as well as heterocumulenes such as an isocyanate and an isothiocyanate. John Wiley and Sons Inc. 2020-05-08 2020-07-06 /pmc/articles/PMC7384015/ /pubmed/32311213 http://dx.doi.org/10.1002/anie.202004651 Text en © 2020 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Communications
Fang, Huaquan
Oestreich, Martin
Reductive Deamination with Hydrosilanes Catalyzed by B(C(6)F(5))(3)
title Reductive Deamination with Hydrosilanes Catalyzed by B(C(6)F(5))(3)
title_full Reductive Deamination with Hydrosilanes Catalyzed by B(C(6)F(5))(3)
title_fullStr Reductive Deamination with Hydrosilanes Catalyzed by B(C(6)F(5))(3)
title_full_unstemmed Reductive Deamination with Hydrosilanes Catalyzed by B(C(6)F(5))(3)
title_short Reductive Deamination with Hydrosilanes Catalyzed by B(C(6)F(5))(3)
title_sort reductive deamination with hydrosilanes catalyzed by b(c(6)f(5))(3)
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384015/
https://www.ncbi.nlm.nih.gov/pubmed/32311213
http://dx.doi.org/10.1002/anie.202004651
work_keys_str_mv AT fanghuaquan reductivedeaminationwithhydrosilanescatalyzedbybc6f53
AT oestreichmartin reductivedeaminationwithhydrosilanescatalyzedbybc6f53

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