Gremlin 1 depletion in vivo causes severe enteropathy and bone marrow failure

The intestinal epithelium is perpetually renewed from a stem cell niche in the base of crypts to maintain a healthy bowel mucosa. Exit from this niche and maturation of epithelial cells requires tightly controlled gradients in BMP signalling, progressing from low BMP signalling at the crypt base to...

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Detalles Bibliográficos
Autores principales: Rowan, Simon C, Jahns, Hanne, Mthunzi, Liberty, Piouceau, Lucie, Cornwell, Joanna, Doody, Róisín, Frohlich, Stephen, Callanan, John J, McLoughlin, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2020
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384058/
https://www.ncbi.nlm.nih.gov/pubmed/32297672
http://dx.doi.org/10.1002/path.5450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384058/
https://www.ncbi.nlm.nih.gov/pubmed/32297672
http://dx.doi.org/10.1002/path.5450

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