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Gremlin 1 depletion in vivo causes severe enteropathy and bone marrow failure

The intestinal epithelium is perpetually renewed from a stem cell niche in the base of crypts to maintain a healthy bowel mucosa. Exit from this niche and maturation of epithelial cells requires tightly controlled gradients in BMP signalling, progressing from low BMP signalling at the crypt base to...

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Detalles Bibliográficos
Autores principales:	Rowan, Simon C, Jahns, Hanne, Mthunzi, Liberty, Piouceau, Lucie, Cornwell, Joanna, Doody, Róisín, Frohlich, Stephen, Callanan, John J, McLoughlin, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2020
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384058/ https://www.ncbi.nlm.nih.gov/pubmed/32297672 http://dx.doi.org/10.1002/path.5450

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