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Human T cells employ conserved AU‐rich elements to fine‐tune IFN‐γ production

Long‐lasting CD8(+) T cell responses are critical in combatting infections and tumors. The pro‐inflammatory cytokine IFN‐γ is a key effector molecule herein. We recently showed that in murine T cells the production of IFN‐γ is tightly regulated through adenylate uridylate–rich elements (AREs) that a...

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Detalles Bibliográficos
Autores principales: Freen‐van Heeren, Julian J., Popović, Branka, Guislain, Aurélie, Wolkers, Monika C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384093/
https://www.ncbi.nlm.nih.gov/pubmed/32112565
http://dx.doi.org/10.1002/eji.201948458