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The Photocatalyzed Thiol‐ene reaction: A New Tag to Yield Fast, Selective and reversible Paramagnetic Tagging of Proteins

Paramagnetic restraints have been used in biomolecular NMR for the last three decades to elucidate and refine biomolecular structures, but also to characterize protein‐ligand interactions. A common technique to generate such restraints in proteins, which do not naturally contain a (paramagnetic) met...

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Detalles Bibliográficos
Autores principales: Denis, Maxime, Softley, Charlotte, Giuntini, Stefano, Gentili, Matteo, Ravera, Enrico, Parigi, Giacomo, Fragai, Marco, Popowicz, Grzegorz, Sattler, Michael, Luchinat, Claudio, Cerofolini, Linda, Nativi, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384118/
https://www.ncbi.nlm.nih.gov/pubmed/32092218
http://dx.doi.org/10.1002/cphc.202000071