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Technical Note: The development of a multi‐physics simulation tool to estimate the background dose by systemic targeted alpha therapy

PURPOSE: To predict biological effects of targeted alpha therapy (TAT) in preclinical studies, dosimetry calculations based on the micro‐level distributions of emitters are essential. Due to the saturation of the tumor antigenic sites and bonding breaks by decay, some of Alpha‐immuno‐conjugate and d...

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Detalles Bibliográficos
Autores principales: Xu, T., Liu, T., Li, G., Dugal, C., Aydemir, N. A., Liu, Y., Roeske, J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384137/
https://www.ncbi.nlm.nih.gov/pubmed/32129888
http://dx.doi.org/10.1002/mp.14111