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Molecular basis for GTP recognition by light‐activated guanylate cyclase RhGC

Cyclic guanosine 3′,5′‐monophosphate (cGMP) is an intracellular signalling molecule involved in many sensory and developmental processes. Synthesis of cGMP from GTP is catalysed by guanylate cyclase (GC) in a reaction analogous to cAMP formation by adenylate cyclase (AC). Although detailed structura...

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Detalles Bibliográficos
Autores principales: Butryn, Agata, Raza, Hadeeqa, Rada, Heather, Moraes, Isabel, Owens, Raymond J., Orville, Allen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384201/
https://www.ncbi.nlm.nih.gov/pubmed/31808997
http://dx.doi.org/10.1111/febs.15167