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CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation

BACKGROUND: The presence of foamy macrophages and microglia containing intracellular myelin remnants is a pathological hallmark of neurodegenerative disorders such as multiple sclerosis (MS). Despite the importance of myelin internalization in affecting both central nervous system repair and neuroin...

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Detalles Bibliográficos
Autores principales: Grajchen, Elien, Wouters, Elien, van de Haterd, Britt, Haidar, Mansour, Hardonnière, Kévin, Dierckx, Tess, Van Broeckhoven, Jana, Erens, Celine, Hendrix, Sven, Kerdine-Römer, Saadia, Hendriks, Jerome J. A., Bogie, Jeroen F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384221/
https://www.ncbi.nlm.nih.gov/pubmed/32718316
http://dx.doi.org/10.1186/s12974-020-01899-x