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CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation
BACKGROUND: The presence of foamy macrophages and microglia containing intracellular myelin remnants is a pathological hallmark of neurodegenerative disorders such as multiple sclerosis (MS). Despite the importance of myelin internalization in affecting both central nervous system repair and neuroin...
Autores principales: | Grajchen, Elien, Wouters, Elien, van de Haterd, Britt, Haidar, Mansour, Hardonnière, Kévin, Dierckx, Tess, Van Broeckhoven, Jana, Erens, Celine, Hendrix, Sven, Kerdine-Römer, Saadia, Hendriks, Jerome J. A., Bogie, Jeroen F. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384221/ https://www.ncbi.nlm.nih.gov/pubmed/32718316 http://dx.doi.org/10.1186/s12974-020-01899-x |
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