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Carbon-11 carboxylation of trialkoxysilane and trimethylsilane derivatives using [(11)C]CO(2)

A novel carboxylation radiosynthesis methodology is described starting from cyclotron-produced [(11)C]CO(2) and fluoride-activated silane derivatives. Six carbon-11 labelled carboxylic acids were obtained from their corresponding trimethylsilyl and trialkoxysilyl precursors in a one-pot labelling me...

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Detalles Bibliográficos
Autores principales: Bongarzone, Salvatore, Raucci, Nicola, Fontana, Igor Camargo, Luzi, Federico, Gee, Antony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384297/
https://www.ncbi.nlm.nih.gov/pubmed/32211652
http://dx.doi.org/10.1039/d0cc00449a