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The CaMKII K42M and K42R mutations are equivalent in suppressing kinase activity and targeting

CaMKII is an important mediator of forms of synaptic plasticity that are thought to underly learning and memory. The CaMKII mutants K42M and K42R have been used interchangeably as research tools, although some reported phenotypic differences suggest that they may differ in the extent to which they i...

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Detalles Bibliográficos
Autores principales: Tullis, Jonathan E., Rumian, Nicole L., Brown, Carolyn Nicole, Bayer, K. Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384616/
https://www.ncbi.nlm.nih.gov/pubmed/32716967
http://dx.doi.org/10.1371/journal.pone.0236478