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Unravelling the γ-butyrolactone network in Streptomyces coelicolor by computational ensemble modelling

Antibiotic production is coordinated in the Streptomyces coelicolor population through the use of diffusible signaling molecules of the γ-butyrolactone (GBL) family. The GBL regulatory system involves a small, and not completely defined two-gene network which governs a potentially bi-stable switch b...

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Detalles Bibliográficos
Autores principales: Tsigkinopoulou, Areti, Takano, Eriko, Breitling, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384680/
https://www.ncbi.nlm.nih.gov/pubmed/32649676
http://dx.doi.org/10.1371/journal.pcbi.1008039