Perturbation biology links temporal protein changes to drug responses in a melanoma cell line

Cancer cells have genetic alterations that often directly affect intracellular protein signaling processes allowing them to bypass control mechanisms for cell death, growth and division. Cancer drugs targeting these alterations often work initially, but resistance is common. Combinations of targeted...

Descripción completa

Detalles Bibliográficos
Autores principales: Nyman, Elin, Stein, Richard R., Jing, Xiaohong, Wang, Weiqing, Marks, Benjamin, Zervantonakis, Ioannis K., Korkut, Anil, Gauthier, Nicholas P., Sander, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384681/
https://www.ncbi.nlm.nih.gov/pubmed/32667922
http://dx.doi.org/10.1371/journal.pcbi.1007909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384681/
https://www.ncbi.nlm.nih.gov/pubmed/32667922
http://dx.doi.org/10.1371/journal.pcbi.1007909

Ejemplares similares