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Perturbation biology links temporal protein changes to drug responses in a melanoma cell line
Cancer cells have genetic alterations that often directly affect intracellular protein signaling processes allowing them to bypass control mechanisms for cell death, growth and division. Cancer drugs targeting these alterations often work initially, but resistance is common. Combinations of targeted...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384681/ https://www.ncbi.nlm.nih.gov/pubmed/32667922 http://dx.doi.org/10.1371/journal.pcbi.1007909 |