Cargando…
The pregnant myometrium is epigenetically activated at contractility-driving gene loci prior to the onset of labor in mice
During gestation, uterine smooth muscle cells transition from a state of quiescence to one of contractility, but the molecular mechanisms underlying this transition at a genomic level are not well-known. To better understand these events, we evaluated the epigenetic landscape of the mouse myometrium...
Autores principales: | Shchuka, Virlana M., Abatti, Luis E., Hou, Huayun, Khader, Nawrah, Dorogin, Anna, Wilson, Michael D., Shynlova, Oksana, Mitchell, Jennifer A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384763/ https://www.ncbi.nlm.nih.gov/pubmed/32667910 http://dx.doi.org/10.1371/journal.pbio.3000710 |
Ejemplares similares
-
MYB and ELF3 differentially modulate labor-inducing gene expression in myometrial cells
por: Shchuka, Virlana M., et al.
Publicado: (2023) -
Matrix Metalloproteinase Expression in the Rat Myometrium During Pregnancy, Term Labor, and Postpartum
por: Nguyen, Tina Tu-Thu Ngoc, et al.
Publicado: (2016) -
Inhibition by sildenafil of contractility of isolated non-pregnant human myometrium
por: Winston, Aruldhas Blessed, et al.
Publicado: (2015) -
The In Vitro Contractile Response of Canine Pregnant Myometrium to Oxytocin and Denaverine Hydrochloride
por: Jungmann, Carolin, et al.
Publicado: (2023) -
Molecular evidence of functional progesterone withdrawal in human myometrium
por: Nadeem, Lubna, et al.
Publicado: (2016)