Activation of PGK1 under hypoxic conditions promotes glycolysis and increases stem cell-like properties and the epithelial-mesenchymal transition in oral squamous cell carcinoma cells via the AKT signalling pathway

Although it has been previously documented that a hypoxic environment can promote glycolysis and the malignant progression of oral squamous cell carcinoma (OSCC) cells, the specific underlying mechanism remains unclear. Phosphoglycerate kinase 1 (PGK1) has been previously reported to serve an import...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yadong, Cai, Hongshi, Liao, Yan, Zhu, Yue, Wang, Fang, Hou, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384853/
https://www.ncbi.nlm.nih.gov/pubmed/32705252
http://dx.doi.org/10.3892/ijo.2020.5083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384853/
https://www.ncbi.nlm.nih.gov/pubmed/32705252
http://dx.doi.org/10.3892/ijo.2020.5083

Ejemplares similares