Cargando…

Activation of PGK1 under hypoxic conditions promotes glycolysis and increases stem cell-like properties and the epithelial-mesenchymal transition in oral squamous cell carcinoma cells via the AKT signalling pathway

Although it has been previously documented that a hypoxic environment can promote glycolysis and the malignant progression of oral squamous cell carcinoma (OSCC) cells, the specific underlying mechanism remains unclear. Phosphoglycerate kinase 1 (PGK1) has been previously reported to serve an import...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yadong, Cai, Hongshi, Liao, Yan, Zhu, Yue, Wang, Fang, Hou, Jinsong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384853/ https://www.ncbi.nlm.nih.gov/pubmed/32705252 http://dx.doi.org/10.3892/ijo.2020.5083

Ejemplares similares

LDHA Promotes Oral Squamous Cell Carcinoma Progression Through Facilitating Glycolysis and Epithelial–Mesenchymal Transition
por: Cai, Hongshi, et al.
Publicado: (2019)

Deregulation of Hexokinase II Is Associated with Glycolysis, Autophagy, and the Epithelial-Mesenchymal Transition in Tongue Squamous Cell Carcinoma under Hypoxia
por: Chen, Guanhui, et al.
Publicado: (2018)

Silencing SHMT2 inhibits the progression of tongue squamous cell carcinoma through cell cycle regulation
por: Liao, Yan, et al.
Publicado: (2021)

Tumor Cell Glycolysis—At the Crossroad of Epithelial–Mesenchymal Transition and Autophagy
por: Marcucci, Fabrizio, et al.
Publicado: (2022)

Esculetin Inhibits Cancer Cell Glycolysis by Binding Tumor PGK2, GPD2, and GPI
por: Wu, Song-Tao, et al.
Publicado: (2020)

FNDC3B promotes epithelial-mesenchymal transition in tongue squamous cell carcinoma cells in a hypoxic microenvironment
por: Zhong, Zhaoming, et al.
Publicado: (2021)

uPAR induces epithelial–mesenchymal transition in hypoxic breast cancer cells
por: Lester, Robin D., et al.
Publicado: (2007)

N6-Methyladenosine Methyltransferase METTL14-Mediated Autophagy in Malignant Development of Oral Squamous Cell Carcinoma
por: Wang, Fang, et al.
Publicado: (2021)

Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma
por: Krisanaprakornkit, Suttichai, et al.
Publicado: (2012)

ACTL6A regulates follicle-stimulating hormone-driven glycolysis in ovarian cancer cells via PGK1
por: Zhang, Jiawen, et al.
Publicado: (2019)

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells
por: Hung, Yin P, et al.
Publicado: (2017)

Activation of adrenergic receptor β2 promotes tumor progression and epithelial mesenchymal transition in tongue squamous cell carcinoma
por: Liu, Haichao, et al.
Publicado: (2018)

ER Stress is Involved in Epithelial-To-Mesenchymal Transition of Alveolar Epithelial Cells Exposed to a Hypoxic Microenvironment
por: Delbrel, Eva, et al.
Publicado: (2019)

O-GlcNAcylation of PGK1 coordinates glycolysis and TCA cycle to promote tumor growth
por: Nie, Hao, et al.
Publicado: (2020)

Epithelial-to-Mesenchymal Transition and Neoangiogenesis in Laryngeal Squamous Cell Carcinoma
por: Franz, Leonardo, et al.
Publicado: (2021)

Cerebroventricular Injection of Pgk1 Attenuates MPTP-Induced Neuronal Toxicity in Dopaminergic Cells in Zebrafish Brain in a Glycolysis-Independent Manner
por: Lin, Cheng-Yung, et al.
Publicado: (2022)

Salinomycin induces cell death and differentiation in head and neck squamous cell carcinoma stem cells despite activation of epithelial-mesenchymal transition and Akt
por: Kuo, Selena Z, et al.
Publicado: (2012)

Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial–mesenchymal transition
por: Irie, Hanna Y., et al.
Publicado: (2005)

PTCSC3‐mediated glycolysis suppresses thyroid cancer progression via interfering with PGK1 degradation
por: Jiang, Bo, et al.
Publicado: (2021)

KIF15 is essential for USP10-mediated PGK1 deubiquitination during the glycolysis of pancreatic cancer
por: Quan, Gang, et al.
Publicado: (2023)

Polarity and epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy
por: Zou, Hui, et al.
Publicado: (2020)

Effects of cisatracurium on epithelial-to-mesenchymal transition in esophageal squamous cell carcinoma
por: Lv, Wenyan, et al.
Publicado: (2019)

Histone deacetylase 3 promotes alveolar epithelial–mesenchymal transition and fibroblast migration under hypoxic conditions
por: Jeong, Sung Hwan, et al.
Publicado: (2022)

Cripto-1 Promotes the Epithelial-Mesenchymal Transition in Esophageal Squamous Cell Carcinoma Cells
por: Huang, Chun, et al.
Publicado: (2015)

Hypoxia Enhances Fusion of Oral Squamous Carcinoma Cells and Epithelial Cells Partly via the Epithelial–Mesenchymal Transition of Epithelial Cells
por: Huang, Chun-ming, et al.
Publicado: (2018)

Norcycloartocarpin targets Akt and suppresses Akt-dependent survival and epithelial-mesenchymal transition in lung cancer cells
por: Nonpanya, Nongyao, et al.
Publicado: (2021)

FGF8 induces epithelial-mesenchymal transition and promotes metastasis in oral squamous cell carcinoma
por: Hao, Yilong, et al.
Publicado: (2021)

Long non-coding RNA NKILA inhibits migration and invasion of tongue squamous cell carcinoma cells via suppressing epithelial-mesenchymal transition
por: Huang, Wei, et al.
Publicado: (2016)

Development and Validation of Autophagy-Related Gene Signature and Nomogram for Predicting Survival in Oral Squamous Cell Carcinoma
por: Hou, Chen, et al.
Publicado: (2020)

AKT3 Expression in Mesenchymal Colorectal Cancer Cells Drives Growth and Is Associated with Epithelial-Mesenchymal Transition
por: Buikhuisen, Joyce Y., et al.
Publicado: (2021)

Epithelial-to-Mesenchymal Transition in the Development and Progression of Adenocarcinoma and Squamous Cell Carcinoma of the Lung
por: Prudkin, Ludmila, et al.
Publicado: (2009)

Hedgehog/Gli promotes epithelial-mesenchymal transition in lung squamous cell carcinomas
por: Yue, Dongsheng, et al.
Publicado: (2014)

Expression of proteins associated with epithelial-mesenchymal transition in esophageal squamous cell carcinoma
por: Zhang, Tian, et al.
Publicado: (2018)

Epithelial-to-Mesenchymal Transition-Derived Heterogeneity in Head and Neck Squamous Cell Carcinomas
por: Baumeister, Philipp, et al.
Publicado: (2021)

Epithelial-mesenchymal transition related to bone invasion in oral squamous cell carcinoma
por: Vanini, Jaqueline Vaz, et al.
Publicado: (2022)

Periostin Facilitates the Epithelial-Mesenchymal Transition of Endometrial Epithelial Cells through ILK-Akt Signaling Pathway
por: Zheng, Qiao-mei, et al.
Publicado: (2016)

lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway
por: Jiang, Qingkun, et al.
Publicado: (2021)

PGK1 contributes to tumorigenesis and sorafenib resistance of renal clear cell carcinoma via activating CXCR4/ERK signaling pathway and accelerating glycolysis
por: He, Yu, et al.
Publicado: (2022)

FERMT1 knockdown inhibits oral squamous cell carcinoma cell epithelial-mesenchymal transition by inactivating the PI3K/AKT signaling pathway
por: Wang, Xiao, et al.
Publicado: (2021)

Evidence for Epithelial-Mesenchymal Transition in Cancer Stem Cells of Head and Neck Squamous Cell Carcinoma
por: Chen, Chao, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_2lui7o8qmvldhoeemdko8kupng