Cargando…

Dexamethasone inhibits stemness maintenance and enhances chemosensitivity of hepatocellular carcinoma stem cells by inducing deSUMOylation of HIF-1α and Oct4

It has been controversial whether patients with hepatocellular carcinoma (HCC) should receive glucocorticoid therapy during chemotherapy. Recent studies have demonstrated that glucocorticoids increase the therapeutic sensitivity of tumors to some chemotherapeutic drugs, but the specific mechanism re...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Zhongmin, Zhang, Chunyan, Liu, Xiaozhi, Ma, Xiaofang, Bian, Xiyun, Xiao, Xiaolin, Gao, Rui, Sun, Yajing, Wu, WenHan, Zhao, Po
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384854/
https://www.ncbi.nlm.nih.gov/pubmed/32705164
http://dx.doi.org/10.3892/ijo.2020.5097