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Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity

T cell cross-reactivity ensures that diverse pathogen-derived epitopes encountered during a lifetime are recognized by the available TCR repertoire. A feature of cross-reactivity where previous exposure to one microbe can alter immunity to subsequent, non-related pathogens has been mainly explored f...

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Detalles Bibliográficos
Autores principales: Mendoza, Juan L, Fischer, Suzanne, Gee, Marvin H, Lam, Lilian H, Brackenridge, Simon, Powrie, Fiona M, Birnbaum, Michael, McMichael, Andrew J, Garcia, K Christopher, Gillespie, Geraldine M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384859/
https://www.ncbi.nlm.nih.gov/pubmed/32716298
http://dx.doi.org/10.7554/eLife.58128