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Phosphoinositides regulate force-independent interactions between talin, vinculin, and actin
Focal adhesions (FA) are large macromolecular assemblies which help transmit mechanical forces and regulatory signals between the extracellular matrix and an interacting cell. Two key proteins talin and vinculin connecting integrin to actomyosin networks in the cell. Both proteins bind to F-actin an...
Autores principales: | Kelley, Charlotte F, Litschel, Thomas, Schumacher, Stephanie, Dedden, Dirk, Schwille, Petra, Mizuno, Naoko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384861/ https://www.ncbi.nlm.nih.gov/pubmed/32657269 http://dx.doi.org/10.7554/eLife.56110 |
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