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TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis
TRAF-interacting protein with a forkhead-associated domain B (TIFAB) is implicated in myeloid malignancies with deletion of chromosome 5q. Employing a combination of proteomic and genetic approaches, we find that TIFAB regulates ubiquitin-specific peptidase 15 (USP15) ubiquitin hydrolase activity. E...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384867/ https://www.ncbi.nlm.nih.gov/pubmed/32101751 http://dx.doi.org/10.1016/j.celrep.2020.01.093 |