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Dicer’s Helicase Domain: A Meeting Place for Regulatory Proteins

The function of Dicer’s helicase domain has been enigmatic since its discovery. Why do only some Dicers require ATP, despite a high degree of sequence conservation in their helicase domains? We discuss evolutionary considerations based on differences between vertebrate and invertebrate antiviral def...

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Detalles Bibliográficos
Autores principales: HANSEN, SARAH R., ADEROUNMU, ADEDEJI M., DONELICK, HELEN M., BASS, BRENDA L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384945/
https://www.ncbi.nlm.nih.gov/pubmed/32179591
http://dx.doi.org/10.1101/sqb.2019.84.039750