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Treatment-resistant nephrotic syndrome in dense deposit disease: complement-mediated glomerular capillary wall injury?

BACKGROUND: The C3 glomerulopathies (C3G) are recently defined glomerular diseases, attributed to abnormal complement regulation. Dense deposit disease (DDD) is part of the spectrum of C3G, characterized by electron-dense deposits in the lamina densa of the glomerular basement membrane. Patients wit...

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Detalles Bibliográficos
Autores principales: Duineveld, Caroline, Steenbergen, Eric J., Bomback, Andrew S., van de Kar, Nicole C. A. J., Wetzels, Jack F. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384995/
https://www.ncbi.nlm.nih.gov/pubmed/32447506
http://dx.doi.org/10.1007/s00467-020-04600-9