Validation tests for cryo-EM maps using an independent particle set

Cryo-electron microscopy (cryo-EM) has revolutionized structural biology by providing 3D density maps of biomolecules at near-atomic resolution. However, map validation is still an open issue. Despite several efforts from the community, it is possible to overfit 3D maps to noisy data. Here, we devel...

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Detalles Bibliográficos
Autores principales: Ortiz, Sebastian, Stanisic, Luka, Rodriguez, Boris A, Rampp, Markus, Hummer, Gerhard, Cossio, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385033/
https://www.ncbi.nlm.nih.gov/pubmed/32743544
http://dx.doi.org/10.1016/j.yjsbx.2020.100032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385033/
https://www.ncbi.nlm.nih.gov/pubmed/32743544
http://dx.doi.org/10.1016/j.yjsbx.2020.100032

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