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Validation tests for cryo-EM maps using an independent particle set
Cryo-electron microscopy (cryo-EM) has revolutionized structural biology by providing 3D density maps of biomolecules at near-atomic resolution. However, map validation is still an open issue. Despite several efforts from the community, it is possible to overfit 3D maps to noisy data. Here, we devel...
Autores principales: | Ortiz, Sebastian, Stanisic, Luka, Rodriguez, Boris A, Rampp, Markus, Hummer, Gerhard, Cossio, Pilar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385033/ https://www.ncbi.nlm.nih.gov/pubmed/32743544 http://dx.doi.org/10.1016/j.yjsbx.2020.100032 |
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