Escherichia coli–Specific CD4+ T Cells Have Public T-Cell Receptors and Low Interleukin 10 Production in Crohn’s Disease

BACKGROUND & AIMS: Crohn’s disease (CD) likely represents decreased immune tolerance to intestinal bacterial antigens. Most CD patients have high titers of antibodies to intestinal commensal proteins, including the outer membrane porin C (OmpC) of Escherichia coli. METHODS: By using major histoc...

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Detalles Bibliográficos
Autores principales: Uchida, Amiko M., Boden, Elisa K., James, Eddie A., Shows, Donna M., Konecny, Andrew J., Lord, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385044/
https://www.ncbi.nlm.nih.gov/pubmed/32361018
http://dx.doi.org/10.1016/j.jcmgh.2020.04.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385044/
https://www.ncbi.nlm.nih.gov/pubmed/32361018
http://dx.doi.org/10.1016/j.jcmgh.2020.04.013

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