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Escherichia coli–Specific CD4+ T Cells Have Public T-Cell Receptors and Low Interleukin 10 Production in Crohn’s Disease

BACKGROUND & AIMS: Crohn’s disease (CD) likely represents decreased immune tolerance to intestinal bacterial antigens. Most CD patients have high titers of antibodies to intestinal commensal proteins, including the outer membrane porin C (OmpC) of Escherichia coli. METHODS: By using major histoc...

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Detalles Bibliográficos
Autores principales:	Uchida, Amiko M., Boden, Elisa K., James, Eddie A., Shows, Donna M., Konecny, Andrew J., Lord, James D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385044/ https://www.ncbi.nlm.nih.gov/pubmed/32361018 http://dx.doi.org/10.1016/j.jcmgh.2020.04.013

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