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The SNCA-Rep1 Polymorphic Locus: Association with the Risk of Parkinson’s Disease and SNCA Gene Methylation

Neurodegeneration in Parkinson’s disease is characterized by the accumulation of alpha-synuclein, a protein encoded by the SNCA gene, in neurons. In addition to mutations, many polymorphisms have been identified in this gene, and one of these is a dinucleotide microsatellite: SNCA-Rep1. The mechanis...

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Detalles Bibliográficos
Autores principales: Iakovenko, E. V., Abramycheva, N. Yu., Fedotova, E. Yu., Illarioshkin, S. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385090/
https://www.ncbi.nlm.nih.gov/pubmed/32742734
http://dx.doi.org/10.32607/actanaturae.10956