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A simple method for detecting oncofetal chondroitin sulfate glycosaminoglycans in bladder cancer urine

Proteoglycans in bladder tumors are modified with a distinct oncofetal chondroitin sulfate (ofCS) glycosaminoglycan that is normally restricted to placental trophoblast cells. This ofCS-modification can be detected in bladder tumors by the malarial VAR2CSA protein, which in malaria pathogenesis medi...

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Detalles Bibliográficos
Autores principales: Clausen, Thomas Mandel, Kumar, Gunjan, Ibsen, Emilie K., Ørum-Madsen, Maj S., Hurtado-Coll, Antonio, Gustavsson, Tobias, Agerbæk, Mette Ø., Gatto, Francesco, Todenhöfer, Tilman, Basso, Umberto, Knowles, Margaret A., Sanchez-Carbayo, Marta, Salanti, Ali, Black, Peter C., Daugaard, Mads
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385127/
https://www.ncbi.nlm.nih.gov/pubmed/32793395
http://dx.doi.org/10.1038/s41420-020-00304-z