SMAC mimetics induce autophagy-dependent apoptosis of HIV-1-infected macrophages

Human immunodeficiency type 1 (HIV)-infected macrophages (HIV-Mφ) are a reservoir for latent HIV infection and a barrier to HIV eradication. In contrast to CD4+ T cells, HIV-Mφ are resistant to the cytopathic effects of acute HIV infection and have increased expression of cell survival factors, incl...

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Detalles Bibliográficos
Autores principales: Campbell, Grant R., To, Rachel K., Zhang, Gang, Spector, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385130/
https://www.ncbi.nlm.nih.gov/pubmed/32719312
http://dx.doi.org/10.1038/s41419-020-02761-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385130/
https://www.ncbi.nlm.nih.gov/pubmed/32719312
http://dx.doi.org/10.1038/s41419-020-02761-x

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