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Anti-allergic rhinitis activity of α-lipoic acid via balancing Th17/Treg expression and enhancing Nrf2/HO-1 pathway signaling

An ovalbumin (OVA)-induced allergic rhinitis (AR) mouse model was established to investigate whether α-Lipoic acid (LA) has a protective effect against upper respiratory tract inflammation. BALB/c mice were sensitized by intraperitoneal injection and challenged by intranasal application of OVA. Mice...

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Detalles Bibliográficos
Autores principales: Van Nguyen, Thi, Piao, Chun Hua, Fan, Yan Jing, Shin, Dong-Uk, Kim, Seung Yong, Song, Hyeon-Ji, Song, Chang Ho, Shin, Hee Soon, Chai, Ok Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385155/
https://www.ncbi.nlm.nih.gov/pubmed/32719431
http://dx.doi.org/10.1038/s41598-020-69234-1