GADD45α drives brown adipose tissue formation through upregulating PPARγ in mice

Stress can lead to obesity and metabolic dysfunction, but the underlying mechanisms are unclear. Here we identify GADD45α, a stress-inducible histone folding protein, as a potential regulator for brown adipose tissue biogenesis. Unbiased transcriptomics data indicate a positive correlation between a...

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Detalles Bibliográficos
Autores principales: You, Wenjing, Xu, Ziye, Sun, Ye, Valencak, Teresa G., Wang, Yizhen, Shan, Tizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385159/
https://www.ncbi.nlm.nih.gov/pubmed/32719383
http://dx.doi.org/10.1038/s41419-020-02802-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385159/
https://www.ncbi.nlm.nih.gov/pubmed/32719383
http://dx.doi.org/10.1038/s41419-020-02802-5

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