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Age-dependent regional retinal nerve fibre changes in SIX1/SIX6 polymorphism

SIX1/SIX6 polymorphism has been shown to be associated with glaucoma. Studies have also found that, in older adults, retinal nerve fibre layer (RNFL) thickness is significantly thinned with each copy of the risk allele in SIX1/SIX6. However, it is not known whether these genetic variants exert their...

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Detalles Bibliográficos
Autores principales: Charng, Jason, Simcoe, Mark, Sanfilippo, Paul G., Allingham, R. Rand, Hewitt, Alex W., Hammond, Chris J., Mackey, David A., Yazar, Seyhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385166/
https://www.ncbi.nlm.nih.gov/pubmed/32719476
http://dx.doi.org/10.1038/s41598-020-69524-8