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Evidence for the Effectiveness of Remdesivir (GS-5734), a Nucleoside-Analog Antiviral Drug in the Inhibition of I (K(M)) or I (K(DR)) and in the Stimulation of I (MEP)

Remdesivir (RDV, GS-5734), a broad-spectrum antiviral drug in the class of nucleotide analogs, has been particularly tailored for treatment of coronavirus infections. However, to which extent RDV is able to modify various types of membrane ion currents remains largely uncertain. In this study, we he...

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Detalles Bibliográficos
Autores principales: Chang, Wei-Ting, Liu, Ping-Yen, Gao, Zi-Han, Lee, Shih-Wei, Lee, Wen-Kai, Wu, Sheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385287/
https://www.ncbi.nlm.nih.gov/pubmed/32792942
http://dx.doi.org/10.3389/fphar.2020.01091