Bacillus subtilis PcrA Couples DNA Replication, Transcription, Recombination and Segregation

Bacillus subtilis PcrA abrogates replication-transcription conflicts in vivo and disrupts RecA nucleoprotein filaments in vitro. Inactivation of pcrA is lethal. We show that PcrA depletion lethality is suppressed by recJ (involved in end resection), recA (the recombinase), or mfd (transcription-coup...

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Detalles Bibliográficos
Autores principales: Moreno-del Alamo, María, Torres, Rubén, Manfredi, Candela, Ruiz-Masó, José A., del Solar, Gloria, Alonso, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385302/
https://www.ncbi.nlm.nih.gov/pubmed/32793628
http://dx.doi.org/10.3389/fmolb.2020.00140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385302/
https://www.ncbi.nlm.nih.gov/pubmed/32793628
http://dx.doi.org/10.3389/fmolb.2020.00140

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