Cargando…

Downregulation of α‐l‐fucosidase 1 suppresses glioma progression by enhancing autophagy and inhibiting macrophage infiltration

α‐l‐Fucosidase 1 (FUCA1), a lysosomal enzyme that catalyses the hydrolytic cleavage of the terminal fucose residue, has been reported to be involved in tumorigenesis. However, the clinical significance and biological roles of FUCA1 in glioma remain largely unknown. We analyzed FUCA1 expression accor...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Lixia, Li, Zhenwei, Song, Sirong, Chen, Qian, Mo, Lidong, Wang, Chen, Fan, Weijia, Yan, Yan, Tong, Xiaoguang, Yan, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385365/
https://www.ncbi.nlm.nih.gov/pubmed/32314457
http://dx.doi.org/10.1111/cas.14427