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Rae1 drives NKG2D binding‐dependent tumor development in mice by activating mTOR and STAT3 pathways in tumor cells
Natural killer group 2 member D (NKG2D) ligands (NKG2DLs) on tumor cells engage NKG2D and mediate killing by NKG2D(+) immune cells. However, tumor cells with high levels of NKG2DLs are still malignant and proliferate rapidly. We investigated the reason for NKG2DL‐expressing cell progression. Tumor c...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385386/ https://www.ncbi.nlm.nih.gov/pubmed/32333709 http://dx.doi.org/10.1111/cas.14434 |