Rae1 drives NKG2D binding‐dependent tumor development in mice by activating mTOR and STAT3 pathways in tumor cells

Natural killer group 2 member D (NKG2D) ligands (NKG2DLs) on tumor cells engage NKG2D and mediate killing by NKG2D(+) immune cells. However, tumor cells with high levels of NKG2DLs are still malignant and proliferate rapidly. We investigated the reason for NKG2DL‐expressing cell progression. Tumor c...

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Detalles Bibliográficos
Autores principales: Zhao, Peiyan, Yang, Lei, Li, Xin, Lu, Wenting, Lu, Fangjie, Wang, Shengnan, Wang, Ying, Hua, Li, Cui, Cuiyun, Dong, Boqi, Yu, Yongli, Wang, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385386/
https://www.ncbi.nlm.nih.gov/pubmed/32333709
http://dx.doi.org/10.1111/cas.14434

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