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β-hydroxybutyrate and hydroxycarboxylic acid receptor 2 agonists activate the AKT, ERK and AMPK pathways, which are involved in bovine neutrophil chemotaxis

Elevated plasma concentrations of the ketone body β-hydroxybutyrate (BHB), an endogenous agonist of the hydroxycarboxylic acid receptor 2 (HCA2), is associated with an increased incidence of inflammatory diseases during lactation in dairy cows. In the early stages of this pathology, an increase in n...

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Detalles Bibliográficos
Autores principales: Carretta, María D., Barría, Yonathan, Borquez, Katherine, Urra, Bárbara, Rivera, Andrés, Alarcón, Pablo, Hidalgo, María A., Burgos, Rafael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385489/
https://www.ncbi.nlm.nih.gov/pubmed/32719460
http://dx.doi.org/10.1038/s41598-020-69500-2