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β-hydroxybutyrate and hydroxycarboxylic acid receptor 2 agonists activate the AKT, ERK and AMPK pathways, which are involved in bovine neutrophil chemotaxis
Elevated plasma concentrations of the ketone body β-hydroxybutyrate (BHB), an endogenous agonist of the hydroxycarboxylic acid receptor 2 (HCA2), is associated with an increased incidence of inflammatory diseases during lactation in dairy cows. In the early stages of this pathology, an increase in n...
Autores principales: | Carretta, María D., Barría, Yonathan, Borquez, Katherine, Urra, Bárbara, Rivera, Andrés, Alarcón, Pablo, Hidalgo, María A., Burgos, Rafael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385489/ https://www.ncbi.nlm.nih.gov/pubmed/32719460 http://dx.doi.org/10.1038/s41598-020-69500-2 |
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