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Antibody drug separation using thermoresponsive anionic polymer brush modified beads with optimised electrostatic and hydrophobic interactions

Antibody drugs play an important role in biopharmaceuticals, because of the specificity for target biomolecules and reduction of side effects. Thus, separation and analysis techniques for these antibody drugs have increased in importance. In the present study, we develop functional chromatography ma...

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Detalles Bibliográficos
Autores principales: Nagase, Kenichi, Ishii, Saki, Ikeda, Koji, Yamada, Sota, Ichikawa, Daiju, Akimoto, Aya Mizutani, Hattori, Yutaka, Kanazawa, Hideko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385495/
https://www.ncbi.nlm.nih.gov/pubmed/32719404
http://dx.doi.org/10.1038/s41598-020-68707-7